Mikellides Protocol

Key Features

Combination Therapy:

Integrates the use of ketamine with repetitive transcranial magnetic stimulation (rTMS).

Target:

Designed to treat resistant psychiatric disorders, with a primary focus on Major Depressive Disorder that does not respond to conventional therapies.

Scientific Basis:

The method is based on the synergy of the two techniques to enhance neuroplasticity and provide faster symptom relief. It was officially presented in the scientific journal Frontiers in Pharmacology in 2025.

Clinical Application:

The protocol is applied in specialized centers in Cyprus.

https://pubmed.ncbi.nlm.nih.gov/40969944/
https://pubmed.ncbi.nlm.nih.gov/41564208/